are the ‘gold standard’ for measuring oxidative stress in the body. Elevated levels may be the result of excessive red meat intake, reduced activity levels, and smoking, and identify risk for atherosclerosis and cancer.
F2-IsoPs are prostaglandin-like compounds formed from the free radical-mediated oxidation of arachidonic acid, and are the ‘gold standard’ for measuring oxidative stress in the body. F2-IsoPs also have potent biological effects associated with inflammation and therefore may mediate chronic disease initiation and progression. Additionally, F2-IsoPs may also act as potent vasoconstrictors via thromboxane formation in the endothelium, and promote platelet activation resulting in thrombus formation.